I am so sick of this roller coaster. One period in my life I am totally anxious and stressed- yet also skinny and healthy.
The minute I go back on SSRIs I start gaining weight. I swear if I even look at food I put on weight.
There is however a proven reason why:
Paxil (my drug of choice- known as Aropax in Australia), like the other drugs in its class, can impede specific enzymes in your liver that allow your metabolism to function correctly. Much like crimping a garden hose impedes the flow of water through it; so paxil and other SSRI's impede certain neuroendocrine system pathways. The two major hormones that regulate metabolism are insulin and leptin. Insulin works mostly within each individual cell, while leptin works between cells. Leptin regulates blood sugar through two different pathways. One controls appetite and fat storage, while the other is responsible for telling the liver what to do with its stored glucose. The fat-cell derived hormone leptin may be the key to weight gain, with or without taking paxil. As a chemical messenger, leptin tells your brain how fat you are, among other things. Leptin causes you to eat less, and it also increases the amount of energy you use (your metabolism). Therefore, it may be one of the most important factors in determining your weight.
Fortunately there seems to be something you can do:
Knowing that taking paxil will inhibit leptin, the easiest solution involves taking omega 3 oils along with vitamin E.
So I'm off tomorrow to sort that out.
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